Monday 27 February 2012

Mirror Neurons by Martha Burns, Ph.D

What is a parent to do to get a child’s brain started out on the right path – to be able to concentrate on one task for extended periods, be able to handle rapidly changing information, and be flexible enough to switch tasks easily?
Well, it turns out the human brain seems to have a strategy: by developing two core capacities during the first few years of life, interactive play and language, the brain seems to become uniquely equipped to build a range of cognitive capacities.  Recent research suggests that a specific area in the frontal lobe – ‘the doing part of the brain’ - begins to wire itself very early in development through imitation of the movements and sounds made by others. This area, the so-called mirror neuron region, allows an infant to watch or listen to other people and respond with imitative or complementary movements or sounds.  
Because this area is the same region, in the left hemisphere, that is responsible for fluent, easy articulated, speech, researchers have speculated that it might have been an evolutionary starting point for development of human language. But, because it is also active in the right hemisphere, it seems to play an important role in social, and perhaps athletic, interaction. In fact, Miella Dapretto and her colleagues at UCLA recently reported research showing that children with autism spectrum disorders, which include a range of disturbances that impact, among other things, social skill development, have observable deficiencies in the mirror neuron system.
There is reason to speculate, based on the research now available, that exercising the mirror system in general, can build a brain that is better equipped for socialization, school, music and athletics. At this time existing research has demonstrated that exercising Broca’s area of the brain (and other areas that are connected to this area through complex cognitive networks), either through natural parental stimulation in infants or through intense specific practice in school-aged children or adults, one can systematically build a brain that is better equipped for many cognitive tasks including language, reading, writing, and math as well as remediate a brain that seems to have deficits or learning disabilities in one or more of these areas.
Every time a parent plays a game like “Patty-cake, Patty-cake” where the child and parent duplicate a routine with actions and a poem or song, the parent is helping the child to exercise the mirror neuron system. Parents have been doing these action/nursery sequences for years, and there are many similar routines in many cultures. Examples of “mirror neuron” routines that have been around and passed on for generations in Western cultures include – “So Big!” where a parent ask the child something like, “How big are you?” and the child and parent respond together holding up their arms in like fashion, “SO BIG!” or, with older children, “Eensie Weensie Spider” where parent and child imitate each other by alternately touching the thumb of one hand to the forefinger of the other hand to emulate the spider climbing up a water spout.
The wonderful thing about these types of routines is that they illustrate how intuitive parents have been for centuries, at identifying and exploiting the natural directions and priorities of brain development. What worries many of us in neuroscience is when parents abandon these time-tested and intuitive interactions with our young children, swayed by technological advances that enhance productivity and drive positive cognitive changes in a mature brain but by abandoning natural parental interactive routines may actually jeopardize the delicate balance of stimulation in the developing brain.
We must exercise caution when adults develop products that appeal to parents with names that inspire confidence like, “Baby Einstein”, if the products have not been subjected to reasonable controlled studies that will help us understand the impact of these activities on young brains. Most companies that develop products for young children do not conduct this type of research because the assumption is that toys and play activities that engage infants and keep them entertained are not harmful. But, unfortunately, that assumption is not warranted. Many of us who put our children in “walkers” or “swings” in the latter part of the twentieth century learned that these “toys” had unintended consequences (i.e., negative effects, on early motor development).
As developmental neuroscientists and other specialists have begun to understand the implications, both positive and negative, of early stimulation on later brain development, those of us in the sciences need to better inform parents and “toy” makers may need to attempt more accountable to parents. In all fairness, however, it may be unreasonable to expect toy makers to conduct independent controlled research studies that we have not even demanded of drug companies. So, the view held by many scientists is that an educated parent can look beyond the hype of advertising and provide for the young child in their care, a fostering environment that is calmly yet convincingly brain-enhancing.
For Further Reading:
The Mirror Neuron System and the Consequences of Its Dysfunction. Marco Iacoboni and Mirella Depretto. Nature Reviews | Neuroscience Volume 7, December 2006
The Mirror Neuron System is More Active During Complementary Compared with Imitative Action. Roger Newman-Norlund, Hein T van Schie, Alexander M J van Zuijlen, and Harold Bekkering. Nature Neuroscience Vol. 10, May 2007
Using Human Brain Lesions to Infer Function: A Relic from a Past Era in the fMRI age? Chris Rorden and Hans-Otto Karnath. Nature Reviews | Neuroscience Vol. 5,  October 2004
Understanding Emotions in Others: Mirror Neuron Dysfunction in Children with Autism Spectrum Disorders. Mirella Depretto, Mari S. Davies, Jennifer H. Pfeifer, Ashley A. Scott, Marian Sigman, Susan Y. Bookheimer, and Marco Iacoboni. Nature Neuroscience Vol. 9,  December 2005
Social Intelligence: The New Science of Human Relationships. Daniel Goleman. NY, NY: Bantam Books, 2006.
Neural Mechanisms of Selective Auditory Attention are Enhanced by Computerized Training: Electrophysiological Evidence from Language-Impaired and Typically Developing Children. Courtney Stevens, Jessica Fanning, Donna Coch, Lisa Sanders,and Helen Neville. Brain Research Vol. 1205, April 2008.

Thursday 16 February 2012

The truth about video games and the brain, by Bill Jenkins Ph.D

We’ve all seen the news reports, but how do video games really affect the brain? The short answer is this: researchers are working on it. While a great many studies have been done, science has a long way to go before we fully understand the impact video games can have.
The brain is a malleable, “plastic” structure that can change and evolve with every stimulus we give it. Whether that stimulus comes from listening to Tchaikovsky, studying Spanish, training in karate, or jumping through the mushroom kingdom in Super Mario Bros. Wii, every single input can affect the wiring of the brain if the conditions are right.
In a December 2011 article in Nature Reviews Neuroscience, six experts in neuroscience and cognitive psychology – Daphne Bavelier, C. Shawn Green, Doug Hyun Han, Perry F. Renshaw, Michael M. Merzenich and Douglas A. Gentile – offer their perspectives on frequently asked questions related to the effects of video games on the brain:
Are there beneficial effects of video games? Does evidence point to improvements in cognitive function? Given the wide variety of game types and the tasks they demand of the brain, this is an extremely complex and layered issue. Han and Renshaw cite studies indicating that game play may improve visual-spatial capacity, visual acuity, task switching, decision making and object tracking. In perception, gaming has been shown to enhance low-level vision, visual attention, processing speed and statistical inference. These skills are not necessarily general improvements in cognitive functioning, but specific skills transferrable to similar tasks. (Gentile)
Does playing video games have negative effects on the brain and behavior? On this issue, the jury is essentially unanimous: intensive play of high-action games has been shown to have negative cognitive effects. Merzenich references studies that indicate such games can create “listlessness and discontent in slower-paced and less stimulating academic, work or social environments.” Research has drawn connections between playing more violent games and an increase in more aggressive thoughts. Games with anti-social or violent content “have been shown to reduce empathy, to reduce stress associated with observing or initiating anti-social actions, and to increase confrontational and disruptive behaviors in the real world.” (ibid)
How strong is the evidence that video games are addictive? While strong evidence is mounting, research is proceeding but still incomplete. According to Han and Renshaw, investigations suggest that “brain areas that respond to game stimuli in patients with on-line game addiction are similar to those that respond to drug cue-induced craving in patients with substance dependence.” In addition, they state that gaming dependence has been shown to create “dysfunction in five domains: academic, social, occupational, developmental and behavioral.” While gaming addiction may differ from other types of addiction, it clearly appears to be a very real issue.
What should the role of video games be in education and rehabilitation? Again, if we come back to the underlying fact that any stimulus can change the brain under the right conditions, video games – a source of stimuli – certainly have a role to play in these areas. The question is, what stimuli are beneficial to which individuals, and how can we customize the gaming experience to give the learner or patient the stimuli that they most need at a given moment? Adaptive technologies that track a user’s responses and present follow-up material based on those response patterns, especially when wielded by an experienced educator or clinician, offer immense potential.
The last question these experts address is: Where is neuroscience headed in this field? Clearly, studies have shown that video games affect and change the brain, both for ill as well as for good. Some researchers, such as neuroscientist Paul Howard-Jones of Bristol University, are already experimenting with ways to harness computer gaming to enhance classroom learning. Future studies are likely to uncover both detrimental effects of video games and significant benefits of their employment as learning and rehabilitation tools.
“Because of their great didactic efficiencies,” says Merzenich, “and because of brain plasticity-based exercises can improve the performance characteristics of the brain of almost every child, these new game-like tools shall be at the core of a schooling revolution.”
For Further reading:
Brains on Video Games. Daphne Bavelier, C. Shawn Green, Doug Hyun Han, Perry F. Renshaw, Michael M. Merzenich and Douglas A. Gentile. Nature Reviews | Neuroscience. Vol. 12, December 2011.
Harnessing Gaming for the Classroom. D.D. Guttenplan. New York Times Europe, January 29, 2012.